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Serial Mediation Effects of Health Consciousness on Depression in Diabetes Patients: The Moderating Role of Gender

Title
Serial Mediation Effects of Health Consciousness on Depression in Diabetes Patients: The Moderating Role of Gender
Alternative Author(s)

Zheng, Dandan ; Suh, Jeongkyo

Keyword
Diabetes ; Depression ; Health Consciousness ; Physical Activity ; Generalized Anxiety Disorder
Publication Year
2025-06-30
Publisher
Korea Institute for Health and Social Affairs
Citation
Health and Social Welfare Review Vol.45 No.2, pp.675-695
Abstract
This study investigated the dual pathways linking health consciousness to depression in diabetic patients, emphasizing serial mediation by physical activity and generalized anxiety disorder (GAD), alongside gender-dependent moderation. Data from the 2022 Korea National Health and Nutrition Examination Survey (KNHANES) were analyzed using SPSS and AMOS. Serial multiple mediation effects were examined via bootstrapping, and multi-group analysis evaluated gender’s moderating role. Among diabetic patients, 6.2% exhibited moderate-to-severe depressive symptoms, with 0.7% meeting criteria for severe depression. Health consciousness exerted both direct and total indirect effects on depression, with physical activity and GAD serving as sequential mediators. Critically, the mediation pathway through physical activity demonstrated the strongest effect, surpassing the GAD-related pathway. Gender significantly moderated three key relationships: (1) between health consciousness and depression, (2) physical activity and depression, and (3) GAD and depression. Male patients showed stronger direct effects of health consciousness on depression reduction, whereas females exhibited greater sensitivity to mediation through physical activity. These findings highlight health consciousness as a pivotal modifiable factor in depression pathogenesis and underscore the necessity of gender-tailored interventions. Clinical implications emphasize dual strategies: enhancing health consciousness to activate protective behaviors and designing sex-specific programs—cognitive-focused approaches for males versus physical activity-integrated interventions for females. This study provides a robust empirical foundation for multidimensional, personalized diabetes care targeting mental health comorbidities.
ISSN
1226-072X
DOI
10.15709/hswr.2025.45.2.675
KIHASA Research
Subject Classification
Health care > Health promotion
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