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Gender differences in anti‑osteoporosis drug treatment after osteoporotic fractures

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dc.contributor.authorYoun Jung
dc.contributor.authorYeonhee Ko
dc.contributor.authorHa Young Kim
dc.contributor.authorYong Chan Ha
dc.contributor.authorYoung‑Kyun Lee
dc.contributor.authorTae‑Young Kim
dc.contributor.authorDong‑soo Choo
dc.contributor.authorSunmee Jang
dc.date.accessioned2020-02-07T04:47:19Z
dc.date.available2020-02-07T04:47:19Z
dc.date.issued2019-01-25
dc.identifier.issn0914-8779
dc.identifier.urihttps://repository.kihasa.re.kr/handle/201002/33730
dc.description.abstractThis study examined differences between men and women in factors affecting anti-osteoporosis drug treatment after osteoporotic fracture. Using a national claims database, we analyzed patients aged 50 years and older who experienced their first osteoporotic fracture between January 1, 2008, and December 31, 2012. We examined whether patients were prescribed anti-osteoporosis drugs within 6 months post-fracture. Factors associated with treatment status were identified using multivariate logistic regression. Among a total of 556,410 patients aged 50 and older, only 37% were prescribed anti-osteoporosis drugs within 6 months post-fracture. Female patients with fractures were more likely to receive pharmacotherapy than male patients (41.7 vs. 19.3%). Older age significantly increased the likelihood of receiving anti-osteoporosis drugs after osteoporotic fracture. For men, the adjusted odds ratio for receiving therapy was greatest in those aged 80 years and older (OR 6.4), and for women, it was largest in those aged 70–79 (OR 3.33). Both men and women were more likely to be prescribed drugs after a spine fracture, with men having significantly greater odds of receiving drug therapy (men, OR 7.1, 95% CI 6.5–7.9; women 4.79, CI 4.63–4.96). Patients with rheumatic disease or other osteoporosis-inducing comorbid disease were more likely to be prescribed anti-osteoporosis drugs. Our findings indicate that a lack of anti-osteoporosis pharmacotherapy after fracture remains a problem in Korea, especially among men, highlighting the need for effective quality improvement interventions to maximize post-fracture treatment rates.
dc.format.extent8
dc.languageeng
dc.publisherSpringer/Japanese Society of for Bone and Mineral Research
dc.titleGender differences in anti‑osteoporosis drug treatment after osteoporotic fractures
dc.typeArticle
dc.type.localArticle(Academic)
dc.subject.keywordFractures
dc.subject.keywordGender differences
dc.subject.keywordPharmacotherapy
dc.subject.keywordPost-fracture treatment
dc.subject.keywordOsteoporosis
dc.contributor.affiliatedAuthorYoun Jung
dc.identifier.doi10.1007/s00774-018-0904-5
dc.identifier.urlhttps://doi.org/10.1007/s00774-018-0904-5
dc.identifier.localIdKIHASA-3083
dc.citation.titleJournal of Bone and Mineral Metabolism
dc.citation.volume37
dc.citation.number1
dc.citation.date2019
dc.citation.startPage134
dc.citation.endPage141
dc.identifier.bibliographicCitationJournal of Bone and Mineral Metabolism, vol. 37, no. 1, pp. 134 - 141
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